Network. Network. Network.
For unemployed candidates, handing out resumes should be a full-time job. The majority of mid- to senior-level positions are filled through networking, so contact absolutely everyone you know in addition to recruiters who are in a position to hire you or share insights. Networking can include
Personal business contacts, people you've worked for or who worked for you
Vendors and sales representatives you've dealt with in the past five years
People listed in the alumni directory of your alma mater
With a solid resume in hand you'll greatly increase your odds of earning a closer look and getting that interview.